SP9.1.7 The effect of the COVID-19 pandemic on Colorectal Cancer (CRC) diagnosis, management and outcomes

Abstract Aim We studied differences in stage, treatment modality, morbidity and mortality, two week wait referrals (2WW) rate of 2WW cancer diagnosis. Method All to the NHS trust colorectal department were analysed their diagnosis any cancer. Using data extracted from Somerset Cancer Database, we compared CRC patients diagnosed 6 months prior (Pre-PAN) following (PAN) national lockdown on 23/02/2020. Outcome measures included: resection rate, stoma Clavien-Dindo score 90 day mortality. Statistical analyses included Chi-squared Mann-Whitney-U tests. Results dropped significantly during pandemic (p=0.02). However, kind was not different (PAN=12.4%, Pre-PAN=11.4%,p=0.89). There fewer diagnoses (Median monthly diagnoses: Pre-Pan=13.5, Pan=8.5 p=0.010). a higher proportion Dukes A cancers Pre-Pan Pan (Pre-PAN=31.3%, PAN=14.3%, p=0.036). B (Pre-PAN=13.8%, PAN=33.9%, p=0.032). no excess or mortality between groups. Conclusion morbidity, demonstrating efficacy COVID surgical protocols. PAN presented with advanced tumour stage. GP group. picked up different. Decreased stage migration may be due loss investigative resource patient factors such as fear precipitating late presentation.